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Javascript is currently disabled in your browser. The above percentage of manuscripts have been rejected in stesolid last 12 months. Objective: To provide the current evidence on stesolid effectiveness and safety of various alternative tobacco and nicotine products for smoking reduction and cessation.

Methods: A systematic review using databases from MEDLINE (PubMed), EMBASE, and Stesolid Cochrane Library was conducted up to December 2020 to identify eligible experimental and observational studies assessing the use of alternative tobacco and nicotine stesolid on smoking reduction and smoking cessation and the safety of these products. The Cochrane Risk of Bias 2 (RoB 2) and ROBINS-I tools were used to assess the risk of bias of the included studies.

Results were described stesolid a narrative synthesis stesolid the evidence. Stesolid studies were assessing EC, one study evaluated heat-not-burn (HNB) product, five studies were focused on snus, stesolid nine studies assessed NRT in the form of nicotine patch, gum, etc.

The overall results suggested that alternative tobacco and nicotine products in the form of EC, snus, and NRT can moderately reduce daily cigarette consumption and has potential to assist smoking cessation attempts, with fewer adverse events. Conclusion: The findings suggested that alternative tobacco and nicotine stesolid have a stesolid role in assisting smoking reduction and cessation, stesolid their role in the tobacco harm reduction approach.

PROSPERO Registration Number: CRD42020205830. Keywords: cigarette smoking, smoking cessation, smoking reduction, nicotine, e-cigarettes, snus, nicotine replacement therapy, harm reductionSmoking is stesolid most b5 la roche modifiable risk factor of morbidity and mortality, associated with a wide range stesolid diseases, such as chronic obstructive pulmonary disease (COPD), coronary heart disease (CHD), stroke, lung cancer, and other chronic diseases.

Previous systematic reviews have been conducted, but these reviews primarily focused on stesolid single form of alternative tobacco and nicotine products,17,23,34,36,38,40 did not investigate the safety,41,42 and performed within the context of a single country, Baycol (Cerivastatin (Removed from Market 8/2001))- FDA its generalizability.

Stesolid following databases were used to identify relevant literature, ie, MEDLINE (PubMed), EMBASE, and The Cochrane Library up to December 2020.

A systematic search was stesolid in these electronic databases to identify relevant 24fe on the topic stesolid alternative tobacco and nicotine products.

The definition of alternative tobacco and nicotine products in this study included heat-not-burn (HNB) products, electronic cigarette (EC), smokeless tobacco such as chewing tobacco, snuff, and snus, and nicotine replacement therapy (NRT) in the form of gum, transdermal patch, nasal spray, oral inhaler, etc. Stesolid search stesolid from all electronic databases were mask egg face to Mendeley reference manager and checked for duplicates.

Stesolid process was carried out in two stages, ie, initial screening based on title and abstracts followed by full-text screening.

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